ASK1 Antikörper

Produktnummer ABIN965600

Produktdetails anti-ASK1 Antikörper

Target: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASK1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Spezifität: ASK1 (Ab-83) antibody detects endogenous levels of ASK1 protein around serine 83.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human ASK1 around the phosphorylation site of serine 83 (G-S-SP-V-G).

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000
IHC: 1:50~1:100.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-ASK1 Antikörper (ABIN965600)

Yuan, Feldman, Sussman, Coppola, Nicosia, Cheng: "AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23432-40, (2003) (PubMed).

Mabuchi, Ohmichi, Kimura, Nishio, Arimoto-Ishida, Yada-Hashimoto, Tasaka, Murata: "Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines." in: Endocrinology, Vol. 145, Issue 1, pp. 49-58, (2003) (PubMed).

Kim, Khursigara, Sun, Franke, Chao: "Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1." in: Molecular and cellular biology, Vol. 21, Issue 3, pp. 893-901, (2001) (PubMed).

Details zu ASK1

Target: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Andere Bezeichnung: ASK1 (MAP3K5 Produkte)

Synonyme: ASK1 antikoerper, MAPKKK5 antikoerper, MEKK5 antikoerper, mitogen-activated protein kinase kinase kinase 5 antikoerper, MUD21.11 antikoerper, MUD21_11 antikoerper, 7420452D20Rik antikoerper, ASK antikoerper, Mekk5 antikoerper, Ask1 antikoerper, RGD1306565 antikoerper, mitogen-activated protein kinase kinase kinase 5 antikoerper, MAP3K5 antikoerper, MAPKKK5 antikoerper, Map3k5 antikoerper, map3k5 antikoerper

Pathways: MAPK Signalweg, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response