APOA5 Antikörper

Produktnummer ABIN7446174

Dieses Monoklonal-Antikörper erkennt spezifisch APOA5 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für APOA5 Antikörper (ABIN7446174)

Target: APOA5 (Apolipoprotein A-V (APOA5))

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser APOA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-APOA5 Antikörper

Spezifität: Ni-NTA purified recombinant human Apoa5 expressed in E. Coli strain BL21 (DE3).

Aufreinigung: Antibodies are purified by protein G affinity chromatography.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: Dilution 1: 1,000- 1: 2,000
Suggested ELISA dilution 1: 4,000
ptimized dilution must be determined by end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: -20 °C

Details zu APOA5

Target: APOA5 (Apolipoprotein A-V (APOA5))

Andere Bezeichnung: APOA5

Hintergrund: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.

Gen-ID: 116519

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism