APOA5 Antikörper

Produktnummer ABIN1724647

Produktdetails anti-APOA5 Antikörper

Target: APOA5 (Apolipoprotein A-V (APOA5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser APOA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human Apoa5 expressed in E. coli.

Klon: 2G1H11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-APOA5 Antikörper (ABIN1724647)

Prieur, Coste, Rodriguez: "The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 25468-80, (2003) (PubMed).

Pennacchio, Olivier, Hubacek, Cohen, Cox, Fruchart, Krauss, Rubin: "An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing." in: Science (New York, N.Y.), Vol. 294, Issue 5540, pp. 169-73, (2001) (PubMed).

Details zu APOA5

Target: APOA5 (Apolipoprotein A-V (APOA5))

Andere Bezeichnung: APOA5 (APOA5 Produkte)

Synonyme: APOAV antikoerper, RAP3 antikoerper, 1300007O05Rik antikoerper, Apoav antikoerper, apo-AV antikoerper, apoA-V antikoerper, APOA5 antikoerper, MGC140487 antikoerper, rap3 antikoerper, apoav antikoerper, apoa-v antikoerper, apolipoprotein A5 antikoerper, apolipoprotein A-V antikoerper, apolipoprotein A5 L homeolog antikoerper, APOA5 antikoerper, Apoa5 antikoerper, apoa5.L antikoerper, apoa5 antikoerper

Hintergrund:

Description: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70 % lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.

Aliases: RAP3, APOAV, APOA-V, MGC126836, MGC126838

Gen-ID: 116519

HGNC: 116519

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism