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PLAP Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PLAP in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN965542

Kurzübersicht für PLAP Antikörper (ABIN965542)

Target

Alle PLAP (ALPP) Antikörper anzeigen
PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Reaktivität

  • 152
  • 23
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 93
  • 63
  • 2
  • 2
Maus

Klonalität

  • 82
  • 75
  • 1
Monoklonal

Konjugat

  • 96
  • 12
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PLAP Antikörper ist unkonjugiert

Applikation

  • 113
  • 70
  • 53
  • 44
  • 29
  • 21
  • 20
  • 20
  • 15
  • 13
  • 12
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon

3E5
  • Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human ALPP expressed in E. Coli.

    Isotyp

    IgG2b
  • Applikationshinweise

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C
  • Llinas, Stura, Ménez, Kiss, Stigbrand, Millán, Le Du: "Structural studies of human placental alkaline phosphatase in complex with functional ligands." in: Journal of molecular biology, Vol. 350, Issue 3, pp. 441-51, (2005) (PubMed).

    Chen, Anderson, Hiroi, Medof: "Proprotein interaction with the GPI transamidase." in: Journal of cellular biochemistry, Vol. 88, Issue 5, pp. 1025-37, (2003) (PubMed).

  • Target

    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

    Andere Bezeichnung

    ALPP

    Hintergrund

    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placentallike form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
    Synonyms: ALP, PALP, PLAP, FLJ61142, ALPP

    Molekulargewicht

    58kDa

    Gen-ID

    250
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