PLAP Antikörper

Produktnummer ABIN965542

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PLAP in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für PLAP Antikörper (ABIN965542)

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 3E5

Produktdetails anti-PLAP Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human ALPP expressed in E. Coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-PLAP Antikörper (ABIN965542)

Llinas, Stura, Ménez, Kiss, Stigbrand, Millán, Le Du: "Structural studies of human placental alkaline phosphatase in complex with functional ligands." in: Journal of molecular biology, Vol. 350, Issue 3, pp. 441-51, (2005) (PubMed).

Chen, Anderson, Hiroi, Medof: "Proprotein interaction with the GPI transamidase." in: Journal of cellular biochemistry, Vol. 88, Issue 5, pp. 1025-37, (2003) (PubMed).

Details zu PLAP

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Andere Bezeichnung: ALPP

Hintergrund: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placentallike form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Synonyms: ALP, PALP, PLAP, FLJ61142, ALPP

Molekulargewicht: 58kDa

Gen-ID: 250