Presenilin 1 Antikörper

Produktnummer ABIN962082

Dieses Anti-Presenilin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Presenilin 1 in WB und ELISA. Geeignet für Human, Maus, Ratte und Xenopus laevis.

Kurzübersicht für Presenilin 1 Antikörper (ABIN962082)

Target: Presenilin 1 (PSEN1)

Reaktivität: Human, Maus, Ratte, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Presenilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Presenilin 1 Antikörper

Spezifität: The immunogenic peptide sequences from Presenilin-1, shows 100 % homology to human, xenopus, mouse and rat Presenilin-1. There is no significant homology with other known proteins. The Presenilin-1 antibody cross-reactivity in other species is not known. The appropriate control immunogenic peptides are also available to confirm specificity of antibodies.

Aufreinigung: Immunoaffinity purified

Immunogen: 15 mer peptide locating to the large hydrophilic loop of human or mouse Presenilin-1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (1:10000 - 1:100000), WB (1:1000 - 1:5000)

Usage: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry. Western Blot: 1:1000-1:5000 for neat serum and 1-10 μg/mL for affinity pure using ECL. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well. Immunoprecipitations: We recommend 5-10 μL neat serum or 1-10 μg affinity pure antibody per 100 μg of tissue. Immunohistochemistry & Immunofluorescence: We recommend the use of affinity purified antibody at 2-20 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Sterile PBS. Resuspend to 100 μL

Konzentration: Lot specific

Buffer: PBS, 0.1 % BSA.

Handhabung: Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu Presenilin 1

Target: Presenilin 1 (PSEN1)

Andere Bezeichnung: PSEN1 / Presenilin 1

Hintergrund: Name/Gene ID: PSEN1
Subfamily: Aspartic A22A
Family: protease

Synonyms: PSEN1, AD3, Alzheimer disease 3, FAD, Protein S182, PS1, S182, PS-1, PSNL1, Presenilin 1, Presenilin-1

Gen-ID: 5663

UniProt: P49768

Pathways: Notch Signalweg, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport