Presenilin 1 Antikörper (N-Term)
Kurzübersicht für Presenilin 1 Antikörper (N-Term) (ABIN2781760)
Target
Alle Presenilin 1 (PSEN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- PSEN1 Antibody - N-terminal region
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Sequenz
- TRKDGQLIYT PFTEDTETVG QRALHSILNA AIMISVIVVM TILLVVLYKY
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PSEN1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PSEN1
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anti-Presenilin 1 (PSEN1) (AA 1-160) antibody
PSEN1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 330-359), (C-Term) antibodyPSEN1 Reaktivität: Human, Maus WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB2257 unconjugated
anti-Presenilin 1 (PSEN1) (pSer310) antibodyKD Validated PSEN1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB4510 unconjugated Recombinant Antibody
anti-Presenilin 1 (PSEN1) (AA 4-218) antibodyPSEN1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) antibodyKD Validated PSEN1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB4515 unconjugated Recombinant Antibody
anti-Presenilin 1 (PSEN1) (Middle Region) antibodyPSEN1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 300-349) antibodyPSEN1 Reaktivität: Human, Maus, Affe, Rind (Kuh), Schwein, Meerschweinchen, Pferd WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 107-156) antibodyPSEN1 Reaktivität: Human, Maus, Ratte, Affe, Schwein, Meerschweinchen, Hund, Fledermaus, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 1-160) antibodyPSEN1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (3rd Intracellular Loop), (AA 345-359) antibodyPSEN1 Reaktivität: Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44201-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Presenilin 1 (PSEN1)
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Andere Bezeichnung
- PSEN1
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Hintergrund
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Background Information: Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form o
Gene Name: Presenilin 1
Alternative Symbols: AD3, FAD, PS1, PS-1, S182, ACNINV3
Protein Name: Presenilin-1
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Molekulargewicht
- 53kDa
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Gen-ID
- 5663
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NCBI Accession
- NP_000012
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UniProt
- P49768
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Pathways
- Notch Signalweg, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Target
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