UBE2D2 Antikörper (C-Term)
Kurzübersicht für UBE2D2 Antikörper (C-Term) (ABIN955424)
Target
Alle UBE2D2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 111-140, C-Term
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Spezifität
- This antibody detects UBE2D2 (C-term).
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Protein A column followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D2
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
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Andere Bezeichnung
- UBE2D2
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Hintergrund
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.Synonyms: E2(17)KB 2, UBC4, UBCH5B, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2
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Gen-ID
- 7322
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NCBI Accession
- NP_003330
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Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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