PITRM1 Antikörper (Middle Region)
Kurzübersicht für PITRM1 Antikörper (Middle Region) (ABIN954153)
Target
Alle PITRM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 497-526, Middle Region
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Aufreinigung
- Protein A column, followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 497-526 amino acids from the Central region of human PITRM1
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))
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Andere Bezeichnung
- PITRM1
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Hintergrund
- ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.Synonyms: KIAA1104, MP1, Metalloprotease 1, Pitrilysin metalloproteinase 1, Presequence protease mitochondrial
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Molekulargewicht
- 117455 Da
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Gen-ID
- 9606
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Pathways
- PI3K-Akt Signalweg, SARS-CoV-2 Protein Interaktom
Target
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