PITRM1 Antikörper (AA 490-518)
Kurzübersicht für PITRM1 Antikörper (AA 490-518) (ABIN656324)
Target
Alle PITRM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 490-518
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- PITRM1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Haltbarkeit
- 6 months
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- PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))
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Andere Bezeichnung
- PITRM1
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Hintergrund
- ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
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Molekulargewicht
- 117413
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Gen-ID
- 10531
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NCBI Accession
- NP_001229236, NP_001229238, NP_055704
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UniProt
- Q5JRX3
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Pathways
- PI3K-Akt Signalweg, SARS-CoV-2 Protein Interaktom
Target
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