PDE1B Antikörper (C-Term)

Produktnummer ABIN954063

Produktdetails anti-PDE1B Antikörper

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Bindungsspezifität: AA 480-508, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse PDE1B (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 480-508 amino acids from the C-terminal region of Human PDE1B

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PDE1B

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Andere Bezeichnung: PDE1B (PDE1B Produkte)

Synonyme: 63kDa antikoerper, Pde1b1 antikoerper, PDE1B1 antikoerper, PDES1B antikoerper, Aop2 antikoerper, phosphodiesterase 1B, Ca2+-calmodulin dependent antikoerper, phosphodiesterase 1B antikoerper, Pde1b antikoerper, PDE1B antikoerper

Hintergrund: Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).Synonyms: 5'-cyclic nucleotide phosphodiesterase 1B, 63 kDa Cam-PDE, Calcium/calmodulin-dependent 3', Cam-PDE 1B, PDE1B1, PDES1B, Phosphodiesterase 1B, Phosphodiesterase-1B calmodulin-dependent

Molekulargewicht: 61380 Da

Gen-ID: 5153

NCBI Accession: NP_000915

Pathways: Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma