PDE1B Antikörper (AA 370-536)

Produktnummer ABIN1845413

Produktdetails anti-PDE1B Antikörper

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Bindungsspezifität: AA 370-536

Reaktivität: Human, Maus, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDE1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Details zu PDE1B

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Andere Bezeichnung: PDE1B (PDE1B Produkte)

Synonyme: 63kDa antikoerper, Pde1b1 antikoerper, PDE1B1 antikoerper, PDES1B antikoerper, Aop2 antikoerper, phosphodiesterase 1B, Ca2+-calmodulin dependent antikoerper, phosphodiesterase 1B antikoerper, Pde1b antikoerper, PDE1B antikoerper

Hintergrund: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily.Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex.This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate.cAMP and cGMP function as key regulators of many important physiological processes.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 61.4 kDa

Gen-ID: 5153

Pathways: Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma