PARP2 Antikörper (N-Term)

Produktnummer ABIN953996

Produktdetails anti-PARP2 Antikörper

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Bindungsspezifität: AA 9-41, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse PARP2 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 9-41 amino acids from the N-terminal region of human PARP2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Andere Bezeichnung: PARP2 (PARP2 Produkte)

Hintergrund: PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.Synonyms: ADPRT2, ADPRTL2, EC=2.4.2.30, NAD(+) ADP-ribosyltransferase 2, PARP 2, PARP-2, Poly [ADP-ribose] polymerase 2, Poly[ADP-ribose] synthetase 2, pADPRT-2

Molekulargewicht: 63397 Da

Gen-ID: 11546

NCBI Accession: NP_033762

Pathways: DNA Reparatur