MUTYH Antikörper (Middle Region)
Kurzübersicht für MUTYH Antikörper (Middle Region) (ABIN953552)
Target
Alle MUTYH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 352-381, Middle Region
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Spezifität
- This antibody recognizes MUTYH.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse
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Aufreinigung
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 352-381aa) of human MUTYH.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MUTYH (MutY Homolog (E. Coli) (MUTYH))
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Andere Bezeichnung
- MUTYH
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Hintergrund
- MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair and initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog
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Gen-ID
- 4595
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NCBI Accession
- NP_001041636
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Pathways
- DNA Reparatur
Target
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