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MUTYH Antikörper (AA 436-535)

MUTYH Reaktivität: Human WB, ELISA, IP, RNAi Wirt: Maus Monoclonal 4D10 unconjugated
Produktnummer ABIN561883
  • Target Alle MUTYH Antikörper anzeigen
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    Bindungsspezifität
    • 16
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 436-535
    Reaktivität
    • 55
    • 38
    • 19
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 49
    • 3
    • 3
    Maus
    Klonalität
    • 52
    • 3
    Monoklonal
    Konjugat
    • 33
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MUTYH Antikörper ist unkonjugiert
    Applikation
    • 30
    • 17
    • 16
    • 13
    • 13
    • 13
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), RNA Interference (RNAi)
    Verwendungszweck
    Mouse monoclonal antibody raised against a partial recombinant MUTYH.
    Sequenz
    KLTYQVYGLA LEGQTPVTTV PPGARWLTQE EFHTAAVSTA MKKVFRVYQG QQPGTCMGSK RSQVSSPCSR KKPRMGQQVL DNFFRSHIST DAHSLNSAAQ
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    MUTYH (AAH03178, 436 a.a. ~ 535 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    4D10
    Isotyp
    IgG1
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Komine, Shimodaira, Takao, Soeda, Zhang, Takahashi, Ishioka: "Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain." in: Human mutation, Vol. 36, Issue 7, pp. 704-11, (2015) (PubMed).

    Shinmura, Goto, Tao, Kato, Suzuki, Nakamura, Matsuda, Yin, Morita, Kono, Sugimura: "Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer." in: Oxidative medicine and cellular longevity, Vol. 2014, pp. 617351, (2014) (PubMed).

    Agustina, Hahm, Han, Tran, Chung, Park, Park, Han: "Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation." in: BMC molecular biology, Vol. 15, pp. 17, (2014) (PubMed).

    Raetz, Xie, Kundu, Brinkmeyer, Chang, David: "Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells." in: Carcinogenesis, Vol. 33, Issue 11, pp. 2301-9, (2012) (PubMed).

    Hahm, Chung, Agustina, Han, Yoon, Park, Kang, Park, Na, Han: "Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells." in: Oncology letters, Vol. 4, Issue 6, pp. 1203-1208, (2012) (PubMed).

    Suzuki, Harashima, Kamiya: "Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine." in: DNA repair, Vol. 9, Issue 5, pp. 542-50, (2010) (PubMed).

    van der Post, Kets, Ligtenberg, van Krieken, Hoogerbrugge: "Immunohistochemistry is not an accurate first step towards the molecular diagnosis of MUTYH-associated polyposis." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 1, pp. 25-9, (2008) (PubMed).

  • Target
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    Andere Bezeichnung
    MUTYH (MUTYH Produkte)
    Synonyme
    MUTYH antikoerper, MGC145569 antikoerper, CYP2C antikoerper, MYH antikoerper, 5730495A01Rik antikoerper, Mutyha antikoerper, Mutyhalpha antikoerper, Mutyhb antikoerper, Mutyhbeta antikoerper, Mutyhc antikoerper, Myh antikoerper, mutY DNA glycosylase antikoerper, mutY homolog (E. coli) antikoerper, A/G-specific adenine DNA glycosylase-like antikoerper, MUTYH antikoerper, mutyh antikoerper, LOC100373318 antikoerper, Mutyh antikoerper
    Hintergrund
    Full Gene Name: mutY homolog (E. coli)
    Synonyms: MGC4416,MYH
    Gen-ID
    4595
    Pathways
    DNA Reparatur
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