MSH2 Antikörper (Middle Region)
Kurzübersicht für MSH2 Antikörper (Middle Region) (ABIN953526)
Target
Alle MSH2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 644-673, Middle Region
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Spezifität
- This antibody recognizes human MSH2.
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Aufreinigung
- Purified through a Protein A column followed by peptide affinity purification
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 644-673aa) of human MSH2.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Andere Bezeichnung
- MSH2
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Hintergrund
- MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.Synonyms: DNA mismatch repair protein Msh2, MutS protein homolog 2
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Molekulargewicht
- 104743 Da
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Gen-ID
- 4436
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NCBI Accession
- NP_000242
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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