IL-10 Antikörper (Middle Region)
-
- Target Alle IL-10 (IL10) Antikörper anzeigen
- IL-10 (IL10) (Interleukin 10 (IL10))
-
Bindungsspezifität
- AA 33-62, Middle Region
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser IL-10 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects human IL10.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Purified through a protein A column; followed by peptide affinity purification.
- Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the center region (between 33-62aa) of human IL10.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IL10 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Andere Bezeichnung
- Interleukin-10 / IL10 (IL10 Produkte)
- Hintergrund
- Interleukin-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.Synonyms: CSIF, Cytokine synthesis inhibitory factor, IL-10, TGIF
- Gen-ID
- 3586
- NCBI Accession
- NP_000563
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
-