HYAL1 Antikörper (C-Term)

Produktnummer ABIN952807

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HYAL1 in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HYAL1 Antikörper (C-Term) (ABIN952807)

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HYAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-HYAL1 Antikörper

Bindungsspezifität: AA 279-309, C-Term

Spezifität: This antibody recognizes Human HYAL1 / Hyaluronidase-1 (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of Human HYAL1 / Hyaluronidase-1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Andere Bezeichnung: HYAL1 / Hyaluronidase-1

Hintergrund: This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Hyal-1, Hyaluronoglucosaminidase-1, LUCA1, Lung carcinoma protein 1

Molekulargewicht: 48368 Da

Gen-ID: 3373

NCBI Accession: NP_695013

Pathways: Glycosaminoglycan Metabolic Process