Growth Hormone 2 Antikörper (N-Term)

Produktnummer ABIN952634

Produktdetails anti-Growth Hormone 2 Antikörper

Target: Growth Hormone 2 (GH2)

Bindungsspezifität: AA 18-45, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human Growth hormone 2 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human Growth hormone 2 Genename: GH2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Growth Hormone 2

Target: Growth Hormone 2 (GH2)

Andere Bezeichnung: Growth Hormone 2 (GH2 Produkte)

Synonyme: GH-V antikoerper, GHL antikoerper, GHV antikoerper, hGH-V antikoerper, growth hormone 2 antikoerper, GH2 antikoerper

Hintergrund: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq].Synonyms: GH2, Growth hormone variant, Placenta-specific growth hormone

Molekulargewicht: 25000 Da

Gen-ID: 2689

NCBI Accession: NP_002050

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus