GFAP Antikörper

Produktnummer ABIN952496

Der Huhn Polyklonal Anti-GFAP-Antikörper wurde für WB, IF und IHC (p) validiert. Er ist geeignet, GFAP in Proben von Human, Ratte und Maus zu detektieren. Es sind 7+ Publikationen verfügbar.

Kurzübersicht für GFAP Antikörper (ABIN952496)

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reaktivität: Human, Ratte, Maus

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser GFAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GFAP Antikörper

Spezifität: Recognizes Glial Fibrillary Acidic Protein (GFAP).

Aufreinigung: Affinity Chromatography using a peptide column.

Immunogen: Recombinant Human GFAP (expressed in bacteria). After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Buffer: 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted in the dark at 2-8 °C.

Referenzen für anti-GFAP Antikörper (ABIN952496)

Venables, Lapasset, Gadea, Fort, Klinck, Irimia, Vignal, Thibault, Prinos, Chabot, Abou Elela, Roux, Lemaitre, Tazi: "MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation." in: Nature communications, Vol. 4, pp. 2480, (2014) (PubMed).

Schoppmann, Ricken, Ilhan-Mutlu, Nirtl, Streubel, Preusser, Birner: "Downregulation of CIC does not associate with overexpression of ETV1 or MAP kinase pathway activation in gastrointestinal stromal tumors." in: Cancer investigation, Vol. 32, Issue 7, pp. 363-7, (2014) (PubMed).

Fofana, Xiao, Thumann, Turek, Zona, Tawar, Grunert, Thompson, Zeisel, Baumert: "A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).

Heid, Rickelt, Zimbelmann, Winter, Schumacher, Dörflinger: "Lipid droplets, perilipins and cytokeratins--unravelled liaisons in epithelium-derived cells." in: PLoS ONE, Vol. 8, Issue 5, pp. e63061, (2013) (PubMed).

Kanemaru, Saitoh: "High-yield expression of mouse Aos1-Uba2-fusion SUMO-activating enzyme, mAU, in a baculovirus-insect cell system." in: Bioscience, biotechnology, and biochemistry, Vol. 77, Issue 7, pp. 1575-8, (2013) (PubMed).

Su, Chao, Huang, Weng, Jeng, Lai: "Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy." in: Journal of virology, Vol. 85, Issue 20, pp. 10561-71, (2011) (PubMed).

Huang, Zhou, Saberwal, Konieczna, Horvath, Katsoulidis, Platanias, Eklund: "Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription." in: Molecular and cellular biology, Vol. 30, Issue 19, pp. 4575-94, (2010) (PubMed).

Details zu GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Andere Bezeichnung: GFAP

Hintergrund: Human GFAP is a 49,749 dalton protein (432 amino acids) expressed by astrocytes of the central nervous system. GFAP is an intermediate filament protein and acts as an intra-cellular structural component of the astrocytic cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Rare mutations of the GFAP gene in humans result in Alexander's disease, one of the leukodystrophies.Synonyms: Glial Fibrillary Acidic Protein

Gen-ID: 2670

NCBI Accession: NP_001229305