FOXA2 Antikörper (Middle Region)

Produktnummer ABIN952361

Der Kaninchen Polyklonal Anti-FOXA2-Antikörper wurde für WB, IF, IHC (p) und EIA validiert. Er ist geeignet, FOXA2 in Proben von Human zu detektieren.

Kurzübersicht für FOXA2 Antikörper (Middle Region) (ABIN952361)

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-FOXA2 Antikörper

Bindungsspezifität: AA 135-164, Middle Region

Spezifität: This antibody recognizes Human FOXA2 / HNF3B (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human FOXA2 / HNF3B

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Andere Bezeichnung: FOXA2 / HNF3B

Hintergrund: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.Synonyms: HNF-3-beta, HNF-3B, Hepatocyte nuclear factor 3-beta, TCF3B, Transcription factor 3B

Molekulargewicht: 48306 Da

Gen-ID: 3170

NCBI Accession: NP_068556

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process