C5AR1 Antikörper

Produktnummer ABIN951421

Dieser Ratte Monoklonal Antikörper detektiert spezifisch C5AR1 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für C5AR1 Antikörper (ABIN951421)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser C5AR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 8D6

Produktdetails anti-C5AR1 Antikörper

Spezifität: This monoclonal antibody detects an epitope on the N terminus (aa 1-15) of the human C5a receptor (also known as CD88) found on human myeloid cells including granulocytes and monocytes/macrophages. It does not bind to tubular epithelial cells in situ under normal or inflammatory conditions. C5aR binds to C5a, a 74 aa peptide cleaved from complement protein C5. C5a receptor has seven transmembrane segments and is a member of the rhodopsin subfamily of G protein coupled receptors.

Aufreinigung: Affinity chromatography on Protein G

Immunogen: RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface Donor: Lou/c rat spleen cells

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Andere Bezeichnung: CD88 / C5R1

Hintergrund: Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1

Gen-ID: 728

NCBI Accession: NP_001727

UniProt: P21730

Pathways: Komplementsystem