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CD55 Antikörper (FITC)

CD55 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal MEM-118 FITC
Produktnummer ABIN94185
  • Target Alle CD55 Antikörper anzeigen
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Reaktivität
    • 116
    • 36
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Non-Human Primate
    Wirt
    • 73
    • 69
    • 6
    • 6
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 89
    • 69
    • 2
    Monoklonal
    Konjugat
    • 75
    • 18
    • 15
    • 12
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD55 Antikörper ist konjugiert mit FITC
    Applikation
    • 98
    • 82
    • 47
    • 39
    • 33
    • 26
    • 16
    • 15
    • 14
    • 13
    • 9
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain extracellular glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.
    Kreuzreaktivität (Details)
    Human, Non-Human Primates
    Aufreinigung
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    HPB-ALL human T cell line
    Klon
    MEM-118
    Isotyp
    IgM
    Top Product
    Discover our top product CD55 Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).

  • Target
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Andere Bezeichnung
    CD55 (CD55 Produkte)
    Synonyme
    CR antikoerper, CROM antikoerper, DAF antikoerper, TC antikoerper, Daf antikoerper, Daf-GPI antikoerper, Daf1 antikoerper, GPI-DAF antikoerper, CD55 molecule (Cromer blood group) antikoerper, CD55 molecule, decay accelerating factor for complement antikoerper, CD55 antikoerper, Cd55 antikoerper
    Hintergrund
    CD55 Molecule (Cromer blood group),CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.,DAF, CROM, CHAPLE
    Gen-ID
    1604
    UniProt
    P08174
    Pathways
    Komplementsystem, Regulation of Leukocyte Mediated Immunity
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