CD55 Antikörper

Produktnummer ABIN6939225

Produktdetails anti-CD55 Antikörper

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD55 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Spezifität: Recognizes a single chain glycoprotein of 70 kDa, identified as CD55. This MAb was clustered in Kobe at the Sixth International Workshop on Human Leukocyte Differentiation Antigens as F429D-9 (N-L120). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. Anti-CD55 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Aufreinigung: Purified by Protein A/G

Immunogen: Human umbilical vein endothelial cells (HUVEC)

Klon: F4-29D9

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Jurkat, HUT-78, K562, YT, U937, MG63 and human lymphocytes. Human lymph nodes and tonsils.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung: CD55 (CD55 Produkte)

Synonyme: CR antikoerper, CROM antikoerper, DAF antikoerper, TC antikoerper, Daf antikoerper, Daf-GPI antikoerper, Daf1 antikoerper, GPI-DAF antikoerper, CD55 molecule (Cromer blood group) antikoerper, CD55 molecule, decay accelerating factor for complement antikoerper, CD55 antikoerper, Cd55 antikoerper

Molekulargewicht: 70kDa

Gen-ID: 1604

UniProt: P08174

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity