MME Antikörper

Produktnummer ABIN93934

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MME in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MME Antikörper (ABIN93934)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MME Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: LT10

Produktdetails anti-MME Antikörper

Verwendungszweck: Anti-Hu CD10 Purified

Spezifität: The antibody LT10 reacts with an extracellular epitope of CD10 (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

Kreuzreaktivität (Details): Other not tested, Human

Aufreinigung: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung: CD10

Hintergrund: Membrane metalloendopeptidase,CD10 (neutral endopeptidase –, NEP, common acute lymphocytic leukemia antigen –, CALLA, membrane metallo-endopeptidase –, MME, enkefalinase) is a 100- kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.,CALLA, Neprilysin, Neutral endopeptidase, Enkephalinase, Atriopeptidase, MME

Gen-ID: 4311

UniProt: P08473

Pathways: RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration