PAPPA Antikörper

Produktnummer ABIN934003

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PAPPA in ELISA, WB und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PAPPA Antikörper (ABIN934003)

Target: PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAPPA Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Klon: 10E2

Produktdetails anti-PAPPA Antikörper

Aufreinigung: Protein A affinity chromatography

Immunogen: PAPPA antibody was raised in mouse using purified human PAPP-A/proMBP complex or purified human atherosclerotic tissue form of PAPP-A as the immunogen.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: PBS, pH 7.4, 0.1 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C

Details zu PAPPA

Target: PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))

Andere Bezeichnung: PAPPA

Hintergrund: Pregnancy-associated plasma protein A, pappalysin 1, also known as PAPPA, is a protein used in screening tests for Down syndrome. PAPPA is a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. Synonyms: Monoclonal PAPPA antibody, Anti-PAPPA antibody, PAPP-A antibody, PAPP A antibody, Pregnancy Associated Plasma Protein A antibody.