IGF1R Antikörper

Produktnummer ABIN932527

Dieser Maus Monoklonal Antikörper detektiert spezifisch IGF1R in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IGF1R Antikörper (ABIN932527)

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGF1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 3C8B1

Produktdetails anti-IGF1R Antikörper

Immunogen: IGF1 R antibody was raised in Mouse using a purified recombinant fragment of IGF1 expressed in E. coli as the immunogen.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Details zu IGF1R

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Andere Bezeichnung: IGF1R

Hintergrund: IGF1R binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-likegrowth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha andbeta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent byenhancing cell survival. Synonyms: Monoclonal IGF1R antibody, Anti-IGF1R antibody, Insulin-like growth factor 1 receptor antibody, CD221 antibody, JTK13 antibody, IGF-I receptor antibody, IGF I receptor antibody, CD221 antigen antibody.

Pathways: RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie