MSH6 Antikörper
Kurzübersicht für MSH6 Antikörper (ABIN931485)
Target
Alle MSH6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Immunogen
- MSH6 antibody was raised in Mouse using a purified recombinant fragment of MSH6 expressed in E. coli as the immunogen.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Andere Bezeichnung
- MSH6
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Hintergrund
- Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair. Synonyms: Monoclonal MSH6 antibody, Anti-MSH6 antibody, Muts Homolog 6 antibody, GTBP antibody, HNPCC5 antibody, HSAP antibody.
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Pathways
- DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
Target
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