HDAC3 Antikörper (AA 224-428)

Produktnummer ABIN931391

Der Maus Monoklonal Anti-HDAC3-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, HDAC3 in Proben von Human zu detektieren.

Kurzübersicht für HDAC3 Antikörper (AA 224-428) (ABIN931391)

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HDAC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 3A7B5

Produktdetails anti-HDAC3 Antikörper

Bindungsspezifität: AA 224-428

Immunogen: HDAC3 antibody was raised in Mouse using a purified recombinant fragment of HDAC3(aa224-428) expressed in E. coli as the immunogen.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Details zu HDAC3

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Andere Bezeichnung: HDAC3

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. Synonyms: Monoclonal HDAC3 antibody, Anti-HDAC3 antibody, Histone Deacetylase 3 antibody, HD3 antibody, RPD3 antibody, RPD3-2 antibody, RPD3 2 antibody.

Pathways: Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development