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ORC6 Antikörper

Der Maus Monoklonal Anti-ORC6-Antikörper wurde für DB und ICC validiert. Er ist geeignet, ORC6 in Proben von Human zu detektieren.
Produktnummer ABIN931160

Kurzübersicht für ORC6 Antikörper (ABIN931160)

Target

Alle ORC6 Antikörper anzeigen
ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Reaktivität

  • 25
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Human

Wirt

  • 16
  • 6
  • 2
  • 1
Maus

Klonalität

  • 19
  • 6
Monoklonal

Konjugat

  • 25
Dieser ORC6 Antikörper ist unkonjugiert

Applikation

  • 23
  • 9
  • 7
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Dot Blot (DB), Immunocytochemistry (ICC)

Klon

2679C2b
  • Kreuzreaktivität

    Human

    Kreuzreaktivität (Details)

    Other species not studied.

    Aufreinigung

    Protein G affinity chromatography

    Immunogen

    ORC6 L antibody was raised in mouse using recombinant Human Origin Recognition Complex, Subunit 6 Like (Yeast) (Orc6 )

    Isotyp

    IgG1
  • Applikationshinweise

    ICC: 2-100 µg/mL
    Optimal conditions should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    Lot specific

    Buffer

    ORC6 L antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • Target

    ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

    Andere Bezeichnung

    ORC6L

    Hintergrund

    The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. Synonyms: Monoclonal ORC6L antibody, Anti-ORC6L antibody, Origin recognition complex subunit 6 antibody, ORC6 antibody.

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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