Fibrillarin Antikörper

Produktnummer ABIN931035

Produktdetails anti-Fibrillarin Antikörper

Target: Fibrillarin (FBL)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibrillarin Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: FBL antibody was raised in mouse using recombinant Human Fibrillarin

Klon: 2350C1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: FBL antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu Fibrillarin

Target: Fibrillarin (FBL)

Andere Bezeichnung: FBL (FBL Produkte)

Synonyme: FIB antikoerper, FLRN antikoerper, RNU3IP1 antikoerper, wu:fb37g12 antikoerper, zgc:56145 antikoerper, zgc:77130 antikoerper, FBL antikoerper, AL022665 antikoerper, CG9888 antikoerper, Dmel\\CG9888 antikoerper, Fibri antikoerper, GCR-6 antikoerper, GCR6 antikoerper, Pen59C5 antikoerper, fib antikoerper, pen59C5 antikoerper, MGC76139 antikoerper, fbl antikoerper, fibrillarin antikoerper, Fibrillarin antikoerper, putative fibrillarin antikoerper, fibrillarin S homeolog antikoerper, FBL antikoerper, fbl antikoerper, Fbl antikoerper, Fib antikoerper, fib1 antikoerper, LMJF_19_0100 antikoerper, fbl.S antikoerper

Hintergrund: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. Synonyms: Monoclonal FBL antibody, Anti-FBL antibody, Fibrillarin antibody, FIB antibody, FLRN antibody, RNU3IP1 antibody.

Pathways: Ribonucleoside Biosynthetic Process