CMA1 Antikörper (C-Term)

Produktnummer ABIN929416

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CMA1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CMA1 Antikörper (C-Term) (ABIN929416)

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CMA1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: CMA1 antibody was raised in rabbit using the C terminal of CMA1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CMA1 Blocking Peptide, (ABIN938181), is also available for use as a blocking control in assays to test for specificity of this CMA1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CMA1

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Andere Bezeichnung: CMA1

Hintergrund: CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. Synonyms: Polyclonal CMA1 antibody, Anti-CMA1 antibody, chymase 1, mast cell antibody, CYH antibody, MCT1 antibody, MGC119890 antibody, MGC119891 antibody, chymase antibody.

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis