alpha Adaptin Antikörper (C-Term)

Produktnummer ABIN929410

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch alpha Adaptin in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für alpha Adaptin Antikörper (C-Term) (ABIN929410)

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Adaptin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-alpha Adaptin Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: AP2 A1 antibody was raised in rabbit using the C terminal of AP2 1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

AP2A1 Blocking Peptide, (ABIN5612095), is also available for use as a blocking control in assays to test for specificity of this AP2A1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu alpha Adaptin

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Andere Bezeichnung: AP2A1

Hintergrund: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. Synonyms: Polyclonal AP2A1 antibody, Anti-AP2A1 antibody, adaptor-related protein complex 2, alpha 1 subunit antibody, ADTAA antibody, AP2-ALPHA antibody, CLAPA1 antibody.

Pathways: Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation