Mre11 Antikörper (Middle Region)

Produktnummer ABIN928874

Produktdetails anti-Mre11 Antikörper

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mre11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: MRE11 A antibody was raised in rabbit using the middle region of MRE11 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

MRE11A Blocking Peptide, catalog no. 33R-7907, is also available for use as a blocking control in assays to test for specificity of this MRE11A antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Mre11

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Andere Bezeichnung: MRE11A (MRE11A Produkte)

Synonyme: wu:faa63d12 antikoerper, zgc:64018 antikoerper, Mre11 antikoerper, Mre11b antikoerper, ATLD antikoerper, HNGS1 antikoerper, MRE11 antikoerper, MRE11B antikoerper, MRE11 homolog A, double strand break repair nuclease antikoerper, MRE11 homolog, double strand break repair nuclease antikoerper, MRE11A homolog A, double strand break repair nuclease antikoerper, mre11a antikoerper, MRE11 antikoerper, Mre11a antikoerper

Hintergrund: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. Synonyms: Polyclonal MRE11A antibody, Anti-MRE11A antibody, MRE11 meiotic recombination 11 homolog A, S. cerevisiae antibody, ATLD antibody, HNGS1 antibody, MRE11 antibody, MRE11B antibody.

Pathways: DNA Reparatur