INHBA Antikörper (N-Term)

Produktnummer ABIN928737

Der Kaninchen Polyklonal anti-INHBA Antikörper (ABIN928737) detektiert spezifisch INHBA in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für INHBA Antikörper (N-Term) (ABIN928737)

Target: INHBA (Inhibin, beta A (INHBA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INHBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-INHBA Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: INHBA antibody was raised in rabbit using the N terminal of INHBA as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

INHBA Blocking Peptide, (ABIN937158), is also available for use as a blocking control in assays to test for specificity of this INHBA antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu INHBA

Target: INHBA (Inhibin, beta A (INHBA))

Andere Bezeichnung: INHBA

Hintergrund: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. Synonyms: Polyclonal INHBA antibody, Anti-INHBA antibody, inhibin, beta A antibody, EDF antibody, FRP antibody.

Pathways: Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagie