GALE Antikörper (Middle Region)

Produktnummer ABIN928723

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GALE in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GALE Antikörper (Middle Region) (ABIN928723)

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GALE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GALE Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: GALE antibody was raised in rabbit using the middle region of GALE as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

GALE Blocking Peptide, (ABIN5613709), is also available for use as a blocking control in assays to test for specificity of this GALE antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu GALE

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Andere Bezeichnung: GALE

Hintergrund: GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild to severe ('generalized' form). Synonyms: Polyclonal GALE antibody, Anti-GALE antibody, UDP-galactose-4-epimerase antibody.

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process