TANK Antikörper (N-Term)

Produktnummer ABIN927715

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TANK in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund und Huhn.

Kurzübersicht für TANK Antikörper (N-Term) (ABIN927715)

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TANK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TANK Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Huhn, Hund

Aufreinigung: Purified

Immunogen: TANK antibody was raised in rabbit using the N terminal of TANK as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

TANK Blocking Peptide, (ABIN937413), is also available for use as a blocking control in assays to test for specificity of this TANK antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TANK

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Andere Bezeichnung: TANK

Hintergrund: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. Synonyms: Polyclonal TANK antibody, Anti-TANK antibody, TRAF family member-associated NFKB activator antibody, I-TRAF antibody, TRAF2 antibody.

Pathways: p53 Signalweg, TLR Signalweg, Activation of Innate immune Response