Glutamate Receptor 1 Antikörper (N-Term)

Produktnummer ABIN927672

Dieses Anti-Glutamate Receptor 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Glutamate Receptor 1 in WB. Geeignet für Human und Maus.

Kurzübersicht für Glutamate Receptor 1 Antikörper (N-Term) (ABIN927672)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: GRIA1 antibody was raised in rabbit using the N terminal of GRIA1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

GRIA1 Blocking Peptide, (ABIN937076), is also available for use as a blocking control in assays to test for specificity of this GRIA1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: GRIA1

Hintergrund: Gria1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Synonyms: Polyclonal Gria1 antibody, Anti-Gria1 antibody, glutamate receptor, ionotropic, AMPA1, alpha 1 antibody, 2900051M01Rik antibody, AI853806 antibody, Glr-1 antibody, Glr1 antibody, GluR-A antibody, GluRA antibody, Glur-1 antibody, Glur1 antibody, HIPA1 antibody.

Pathways: PI3K-Akt Signalweg