CCR5 Antikörper (Middle Region)
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- Target Alle CCR5 Antikörper anzeigen
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CCR5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Maus
- Aufreinigung
- Purified
- Immunogen
- CCR5 antibody was raised in rabbit using the middle region of CCR5 as the immunogen
- Top Product
- Discover our top product CCR5 Primärantikörper
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- Applikationshinweise
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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CCR5 Blocking Peptide, catalog no. 33R-8508, is also available for use as a blocking control in assays to test for specificity of this CCR5 antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Andere Bezeichnung
- CCR5 (CCR5 Produkte)
- Synonyme
- CC-CKR-5 antikoerper, CCCKR5 antikoerper, CCR-5 antikoerper, CD195 antikoerper, CKR-5 antikoerper, CKR5 antikoerper, CMKBR5 antikoerper, IDDM22 antikoerper, Ckr5 antikoerper, Cmkbr5 antikoerper, CCR1-L antikoerper, GPCR antikoerper, CCR5 antikoerper, AM4-7 antikoerper, C-C motif chemokine receptor 5 (gene/pseudogene) antikoerper, chemokine (C-C motif) receptor 5 antikoerper, C-C motif chemokine receptor 5 antikoerper, CCR5 antikoerper, Ccr5 antikoerper
- Hintergrund
- CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this protein was also detected in a promyeloblastic cell line, suggesting that CCR5 may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Synonyms: Polyclonal CCR5 antibody, Anti-CCR5 antibody, chemokine, C-C motif receptor 5 antibody, CC-CKR-5 antibody, CCCKR5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody.
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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