TRAF1 Antikörper (Middle Region)

Produktnummer ABIN926936

Der Kaninchen Polyklonal Anti-TRAF1-Antikörper wurde für WB validiert. Er ist geeignet, TRAF1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für TRAF1 Antikörper (Middle Region) (ABIN926936)

Target: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRAF1 Antikörper

Bindungsspezifität: Middle Region

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: TRAF1 antibody was raised in rabbit using the middle region of TRAF1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

TRAF1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TRAF1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TRAF1

Target: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Andere Bezeichnung: TRAF1

Hintergrund: This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Synonyms: Polyclonal TRAF1 antibody, Anti-TRAF1 antibody, TNF receptor-associated factor 1 antibody, EBI6 antibody, MGC:10353 antibody.

Pathways: NF-kappaB Signalweg, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization