NME1 Antikörper (N-Term)

Produktnummer ABIN926849

Der Kaninchen Polyklonal Anti-NME1-Antikörper wurde für WB validiert. Er ist geeignet, NME1 in Proben von Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Huhn, Xenopus laevis und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für NME1 Antikörper (N-Term) (ABIN926849)

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Huhn, Xenopus laevis, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NME1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NME1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Hund, Rind (Kuh), Zebrafisch (Brachydanio rerio), Huhn, Schwein, Frosch

Aufreinigung: Purified

Immunogen: NME1 antibody was raised in rabbit using the N terminal of NME1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

NME1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NME1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu NME1

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Andere Bezeichnung: NME1

Hintergrund: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Synonyms: Polyclonal NME1 antibody, Anti-NME1 antibody, non-metastatic cells 1, protein, NM23A expressed in antibody, AWD antibody, GAAD antibody, NDPKA antibody, NM23 antibody, NM23-H1 antibody.

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process