IGF1R Antikörper (Middle Region)

Produktnummer ABIN926846

Der Kaninchen Polyklonal Anti-IGF1R-Antikörper wurde für WB und IHC validiert. Er ist geeignet, IGF1R in Proben von Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Huhn, Schwein und Xenopus laevis zu detektieren.

Kurzübersicht für IGF1R Antikörper (Middle Region) (ABIN926846)

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Huhn, Schwein, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGF1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-IGF1R Antikörper

Bindungsspezifität: Middle Region

Kreuzreaktivität: Maus, Ratte (Rattus), Schwein, Rind (Kuh), Huhn, Zebrafisch (Brachydanio rerio), Frosch

Aufreinigung: Purified

Immunogen: IGF1 R antibody was raised in rabbit using the middle region of IGF1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

IGF1R Blocking Peptide, (ABIN937530), is also available for use as a blocking control in assays to test for specificity of this IGF1R antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu IGF1R

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Andere Bezeichnung: IGF1R

Hintergrund: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Synonyms: Polyclonal IGF1R antibody, Anti-IGF1R antibody, insulin-like growth factor 1 receptor antibody, CD221 antibody, IGFIR antibody, JTK13 antibody, MGC142170 antibody, MGC142172 antibody, MGC18216 antibody.

Pathways: RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie