Factor XI Antikörper (C-Term)

Produktnummer ABIN926655

Dieses Anti-Factor XI-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Factor XI in WB. Geeignet für Human.

Kurzübersicht für Factor XI Antikörper (C-Term) (ABIN926655)

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor XI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Factor XI Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: F11 antibody was raised in rabbit using the C terminal of F11 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

F11 Blocking Peptide, (ABIN5613441), is also available for use as a blocking control in assays to test for specificity of this F11 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Factor XI

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Andere Bezeichnung: F11

Hintergrund: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. Synonyms: Polyclonal F11 antibody, Anti-F11 antibody, coagulation factor XI antibody, FXI antibody, MGC141891 antibody.