Factor XI Antikörper (Middle Region)

Produktnummer ABIN951607

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Factor XI in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Factor XI Antikörper (Middle Region) (ABIN951607)

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor XI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Factor XI Antikörper

Bindungsspezifität: AA 288-315, Middle Region

Spezifität: This antibody recognizes Human Coagulation factor XI (F11) (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 288-315 amino acids from the Central region of human F11.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Factor XI

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Hintergrund: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].Synonyms: FX1, PTA, Plasma thromboplastin antecedent

Molekulargewicht: 70109 Da

Gen-ID: 2160

NCBI Accession: NP_000119