Hexokinase 1 Antikörper (N-Term)

Produktnummer ABIN926654

Der Kaninchen Polyklonal Anti-Hexokinase 1-Antikörper wurde für WB validiert. Er ist geeignet, Hexokinase 1 in Proben von Human zu detektieren.

Kurzübersicht für Hexokinase 1 Antikörper (N-Term) (ABIN926654)

Target: Hexokinase 1 (HK1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hexokinase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Hexokinase 1 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: HK1 antibody was raised in rabbit using the N terminal of HK1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

HK1 Blocking Peptide, (ABIN937173), is also available for use as a blocking control in assays to test for specificity of this HK1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Hexokinase 1

Target: Hexokinase 1 (HK1)

Andere Bezeichnung: HK1

Hintergrund: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. Synonyms: Polyclonal HK1 antibody, Anti-HK1 antibody, hexokinase 1 antibody, HK1-ta antibody, HK1-tb antibody, HK1-tc antibody, HKI antibody, HXK1 antibody.

Pathways: Carbohydrate Homeostasis, Warburg Effekt