Hexokinase 1 Antikörper

Produktnummer ABIN969194

Produktdetails anti-Hexokinase 1 Antikörper

Target: Hexokinase 1 (HK1)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Hexokinase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human HK1 expressed in E. coli.

Klon: 7A7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Hexokinase 1 Antikörper (ABIN969194)

Martins-de-Souza, Gattaz, Schmitt, Rewerts, Marangoni, Novello, Maccarrone, Turck, Dias-Neto: "Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 116, Issue 3, pp. 275-89, (2009) (PubMed).

Tsai: "Function of interdomain alpha-helix in human brain hexokinase: covalent linkage and catalytic regulation between N- and C-terminal halves." in: Journal of biomedical science, Vol. 14, Issue 2, pp. 195-202, (2007) (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

Details zu Hexokinase 1

Target: Hexokinase 1 (HK1)

Andere Bezeichnung: HK1 (HK1 Produkte)

Synonyme: HK1-ta antikoerper, HK1-tb antikoerper, HK1-tc antikoerper, HKD antikoerper, HKI antikoerper, HMSNR antikoerper, HXK1 antikoerper, Hexokinase antikoerper, hk1 antikoerper, HEX antikoerper, HEX-1 antikoerper, HK antikoerper, ARABIDOPSIS THALIANA HEXOKINASE 1 antikoerper, ATHXK1 antikoerper, F19B15.160 antikoerper, F19B15_160 antikoerper, GIN2 antikoerper, GLUCOSE INSENSITIVE 2 antikoerper, HEXOKINASE antikoerper, hexokinase 1 antikoerper, im:7148527 antikoerper, wu:fc09d08 antikoerper, wu:fc16e02 antikoerper, wu:fc21e02 antikoerper, wu:fq14b11 antikoerper, zgc:55790 antikoerper, zgc:77618 antikoerper, hexokinase-1 antikoerper, HK1 antikoerper, BB404130 antikoerper, Hk-1 antikoerper, Hk1-s antikoerper, dea antikoerper, mHk1-s antikoerper, HEXOKIN antikoerper, Hxk1 antikoerper, NtHxK1 antikoerper, NtHxk antikoerper, hexokinase antikoerper, StHK1 antikoerper, hxk antikoerper, hk1-A antikoerper, hexokinase 1 antikoerper, hexokinase-1 antikoerper, Hexokinase 1 antikoerper, hexokinase 1, putative antikoerper, hexokinase 1 L homeolog antikoerper, HK1 antikoerper, hk1 antikoerper, LOC100136279 antikoerper, Hex1 antikoerper, HXK1 antikoerper, Hk1 antikoerper, TA19800 antikoerper, hxk1 antikoerper, LOC107797523 antikoerper, LOC102604144 antikoerper, hk1.L antikoerper

Hintergrund:

Description: The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.

Aliases: HKI, HXK1, HK1-ta, HK1-tb, HK1-tc, HK1

Molekulargewicht: 102 kDa

Gen-ID: 3098

HGNC: 3098

Pathways: Carbohydrate Homeostasis, Warburg Effekt