MAPKAP Kinase 3 Antikörper (C-Term)

Produktnummer ABIN926459

Der Kaninchen Polyklonal anti-MAPKAP Kinase 3 Antikörper wird verwendet zum Nachweis von MAPKAP Kinase 3 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für MAPKAP Kinase 3 Antikörper (C-Term) (ABIN926459)

Target: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKAP Kinase 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAPKAP Kinase 3 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: MAPKAPK3 antibody was raised in rabbit using the C terminal of MAPKAPK3 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

MAPKAPK3 Blocking Peptide, (ABIN939713), is also available for use as a blocking control in assays to test for specificity of this MAPKAPK3 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu MAPKAP Kinase 3

Target: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Andere Bezeichnung: MAPKAPK3

Hintergrund: MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Synonyms: Polyclonal MAPKAPK3 antibody, Anti-MAPKAPK3 antibody, mitogen-activated protein kinase-activated protein kinase 3 antibody, 3PK antibody, MAPKAP3 antibody.

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades