RAD17 Antikörper (C-Term)

Produktnummer ABIN925763

Produktdetails anti-RAD17 Antikörper

Target: RAD17

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund

Immunogen: RAD17 antibody was raised in rabbit using the C terminal of RAD17 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

RAD17 Blocking Peptide, catalog no. 33R-7392, is also available for use as a blocking control in assays to test for specificity of this RAD17 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RAD17

Target: RAD17

Andere Bezeichnung: RAD17 (RAD17 Produkte)

Hintergrund: RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. Synonyms: Polyclonal RAD17 antibody, Anti-RAD17 antibody, RAD17 homolog, S. pombe antibody, CCYC antibody, HRAD17 antibody, R24L antibody, RAD17Sp antibody, Rad24 antibody.