SETDB2 Antikörper (AA 21-120) (Biotin)
Kurzübersicht für SETDB2 Antikörper (AA 21-120) (Biotin) (ABIN891343)
Target
Alle SETDB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 21-120
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Kreuzreaktivität
- Ratte
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Homologie
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CLLD8/SETDB2
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
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Andere Bezeichnung
- CLLD8
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Hintergrund
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Synonyms: Histone-lysine N-methyltransferase SETDB2, C13orf4, Chromosome 13 open reading frame 4, Chronic lymphocytic leukemia deletion region 8, Chronic lymphocytic leukemia deletion region gene 8, Chronic lymphocytic leukemia deletion region gene 8 protein, Clld8, CLLL8, Gm293, H3-K9-HMTase, Histone H3-K9 methyltransferase, KMT1F, Lysine N-methyltransferase 1F, Probable histone-lysine N-methyltransferase H3 lysine-9 specic, SEB2, SET domain burcated 2, SET domain protein, burcated, 2, SETB2_HUMAN, Setdb2.
Background: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
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Gen-ID
- 83852
Target
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