SETDB2 Antikörper (AA 1-280)
Kurzübersicht für SETDB2 Antikörper (AA 1-280) (ABIN6147657)
Target
Alle SETDB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-280
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Sequenz
- MGEKNGDAKT FWMELEDDGK VDFIFEQVQN VLQSLKQKIK DGSATNKEYI QAMILVNEAT IINSSTSIKD PMPVTQKEQE NKSNAFPSTS CENSFPEDCT FLTTENKEIL SLEDKVVDFR EKDSSSNLSY QSHDCSGACL MKMPLNLKGE NPLQLPIKCH FQRRHAKTNS HSSALHVSYK TPCGRSLRNV EEVFRYLLET ECNFLFTDNF SFNTYVQLAR NYPKQKEVVS DVDISNGVES VPISFCNEID SRKLPQFKYR KTVWPRAYNL TNFSSMFTDS
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SETDB2 (NP_001153780.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
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Andere Bezeichnung
- SETDB2
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Hintergrund
- This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.,SETDB2,C13orf4,CLLD8,CLLL8,KMT1F,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,SETDB2
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Molekulargewicht
- 80 kDa/81 kDa
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Gen-ID
- 83852
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UniProt
- Q96T68
Target
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