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SETDB2 Antikörper (N-Term)

SETDB2 Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258755
  • Target Alle SETDB2 Antikörper anzeigen
    SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
    Bindungsspezifität
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 18
    • 16
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 27
    • 4
    • 1
    Kaninchen
    Klonalität
    • 29
    • 4
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SETDB2 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 13
    • 13
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    SETDB2 Antibody detects endogenous levels of total SETDB2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SETDB2, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product SETDB2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
    Andere Bezeichnung
    SETDB2 (SETDB2 Produkte)
    Synonyme
    C13orf4 antikoerper, CLLD8 antikoerper, CLLL8 antikoerper, KMT1F antikoerper, Clld8 antikoerper, Gm293 antikoerper, SET domain bifurcated 2 antikoerper, SET domain, bifurcated 2 antikoerper, SETDB2 antikoerper, Setdb2 antikoerper
    Hintergrund

    Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.

    Gene: SETDB2

    Molekulargewicht
    120 kDa
    Gen-ID
    83852
    UniProt
    Q96T68
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